CALL FOR APPLICATIONS FOR THE M-HIRST PILOT GRANT-IMPACT OF COVID-19 ON HIV SERVICE DELIVERY AND PATIENT OUTCOMES

INTRODUCTION

The College of Medicine (CoM) was established in 1991 as a constituent college of the University of Malawi with a mission “to be an academic centre of excellence in the training of doctors and other health professionals in clinical service and medical research, responsive to the health needs of Malawi and its neighbours within the Southern African region”. Since 2015, the National Institutes of Health-Fogarty International Centre in the USA has been funding the CoM and University of North Carolina to establish and roll-out the Malawi HIV Implementation Science Research Training (M-HIRST) Program which aims at building and strengthening local capacity for conducting implementing research studies to generate evidence that accelerates the scale of recommended HIV interventions.

 

The Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2, COVID-19) pandemic continues to have serious health and other socio-economic consequences. On April 2nd 2020, the first case of the SARS-CoV-2 infection was registered in Malawi. As of 17th May 2020, 70 cases have been identified and 3 people have died.  In response, the Malawi government and other local stakeholders are implementing a combination of measures to curtail the epidemic in Malawi. While well-intentioned, the measures may affect the quality of HIV service delivery and Malawi’s ambitious goal of achieving 95-95-95[1] by the year 2025. The M-HIRST program is seeking applications from academics or research scientists employed at academic and research institutions in Malawi to implement preliminary HIV implementation research studies that generate data on the impact of COVID-19 on HIV service delivery and patient outcomes. The projects should focus on identifying and characterizing barriers against HIV testing, Antiretroviral Therapy (ART) initiation, retention in HIV care, clinical or supportive care of People Living with HIV (PLHIV), diagnosis of HIV-related co-morbidities, treatment adherence and achieving virological suppression.

ELIGIBILITY

You can apply for this small grant if you fulfill the following criteria:

  1. Currently enrolled in or completed a health-related postgraduate training program;
  2. Have a supervisor or mentor with strong background in HIV research or service delivery;
  3. Employed in an academic or a research institution in Malawi;
  4. Have strong linkages with public institutions or non-governmental institutions which have a track history of delivering HIV services.

Applicants with a history of prior HIV-related publications will have an added advantage.

BUDGET

The maximum budget for each application should be US$10,000. We aim to award grants to 5-10 successful applicants.

 

APPLICATION PROCESS

Interested applicants are required to do the following;

  • Download the attached small grants application template to prepare their applications.
  • Seek a letter of support and bio sketch from a senior academic or public health/clinical health practitioner with a track history in HIV-related research who will provide oversight in research implementation
  • Submit their updated bio sketch to the CoM M-HIRST Project Coordinator – (mhirstcoordinator@medcol.mw).  

The deadline for receiving applications will be on Monday, 15th June 2020 at 23:59 hrs. Applicants will be informed about the outcomes of their applications by 30th June 2020. Ideally, data collection for the research project should be completed by 31st March 2021.

 

ASCEND LEARNING & INNOVATION FUND

Do you have an innovative idea to help beat neglected tropical diseases?

The Ascend West and Central Africa programme, funded by the UK Department for International Development (DFID), is excited to announce the launch of a new learning and innovation fund to accelerate the control and elimination efforts for up to five neglected tropical diseases (NTDs) – lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminths and trachoma.

 

Impact of COVID-19

In response to the pandemic, on 1st April 2020 the World Health Organization (WHO) issued guidance on NTD Programmes – WHO have asked for NTD-community based surveys, active case-finding activities, and mass treatment campaigns to be postponed.

 

The Ascend Learning and Innovation Fund is monitoring the situation closely – this is not about cancelling NTD programmes but delaying activities. Throughout the life of the fund, we will closely liaise with governments and partners, follow national and international guidance and remain flexible in the rapidly changing circumstances.

 

We have added a COVID-19 specific challenge statement and are now proactively seeking proposals which can repurpose NTD platforms to support the COVID-19 response, where appropriate, as well as proposals which will support the recovery of NTD programmes once WHO has advised it is safe to resume elimination activities.

 

What does the fund offer?

The fund provides grants ranging in value from £20,000 – £500,000 to support a flexible range of NTD-focused activities, from research projects to large-scale implementation projects, across 13 countries in West and Central Africa (Benin, Burkina Faso, Central African Republic, Chad, Cote d’Ivoire, Democratic Republic of the Congo, Ghana, Guinea, Guinea Bissau, Liberia, Niger, Nigeria and Sierra Leone).

 

We recognise that the fight against NTDs requires investment in new, evidence-based ideas to improve treatments, interventions and the strength of health systems so we can reach everyone in need, globally.

 

The fund offers the opportunity to be creative and do things differently – to explore innovations, respond to emerging gaps, solve identified needs, and transition operational findings into scalable programming.

 

If you have a fantastic evidence-based idea, we want to hear about it and help turn it into a project. We are seeking proposals that address one of the five following challenge statements:

  • Challenge 1: COVID-19 Response – How can NTD programming provide entry points for COVID-19 response and readiness? (Please note that project proposals responding to COVID-19 will be prioritised in Cycle 1)
  • Challenge 2: Collaboration and multisectoral action – How can NTD interventions leverage synergies arising from collaborations across diseases, sectors and borders?
  • Challenge 3: Universal Health Coverage (UHC) – How can we enhance access to, and quality of, NTD treatment and prevention services in the context of UHC?
  • Challenge 4: Health systems strengthening – How can we ensure long-term, in-country sustainability for NTD programmes?
  • Challenge 5: Data systems – How can we increase the quality and availability of NTD data at all levels to better inform NTD programming?

If you have identified a challenge that falls outside of the above that is relevant to the control and elimination of NTDs, we still want to know. Please send an email to fundteam@ascendwest-innovationfund.org to discuss further.

The Fund consists of 5 application windows. Applications for Cycle 1 are open as of late April 2020 and will close on 29th May 2020. Cycles 1-4 will be open to all applicants; Cycle 5 will be restricted to existing projects or partners. All project activities and reports will have to be completed and submitted by 31st March 2022 at the latest.

Do you want to take your idea to reality?
For more information on the application process, fund guidelines and challenge statements please visit: www.ascendwest-innovationfund.org or email the team on fundteam@ascendwest-innovationfund.org

FUNDING OPPORTUNITIES

 FUNDING OPPORTUNITIES

 

  • National Cancer Institute Program Project Applications (P01 Clinical Trial Optional)

With this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites applications for investigator-initiated Program Project (P01) applications. The proposed Program may address any of the broad areas of cancer research, including (but not limited to) cancer biology, cancer prevention, cancer diagnosis, cancer treatment, and cancer control. Basic, translational, clinical, and/or population-based studies in all of these research areas are appropriate. Each application submitted in response to this FOA must consist of at least three research projects and an Administrative Core. The projects must share a common central theme, focus, and/or overall objective.  

Link: https://grants.nih.gov/grants/guide/pa-files/PAR-20-077.html

Application date line: The first standard due date for this FOA is May 25, 2020  

All applicants are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s). Applicants are encouraged to apply corrections to errors found in the application during the submission process by the due date..

 

  • National Alzheimer’s Coordinating Center 

This FOA invites applications for a National Alzheimer’s Coordinating Center (NACC) whose purpose is to serve NIA and the Alzheimer’s disease and Alzheimer’s disease-related dementias (AD/ADRD) field as 1) a national data resource, collecting data from the Alzheimer’s Disease Research Centers (ADRCs), affiliated data, and sample repositories; 2) a facilitator of current and future AD/ADRD research; and 3) the central hub for organizing and enabling communication within and outside the ADRC program, including annual meetings and steering committees.

Link: https://grants.nih.gov/grants/guide/rfa-files/RFA-AG-21-014.html

Application Date Line: June 17, 2020

No late applications will be accepted for this Funding Opportunity Announcement. All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s).

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

 

  • Childhood Asthma in Urban Settings -Clinical Research Centers

 

The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for the NIAID Childhood Asthma in Urban Settings Clinical Research Network Clinical Research Centers (CAUSE-CRCs). The CAUSE-CRCs will conduct both network-wide and site-specific clinical studies and trials with the ultimate goal of developing effective asthma treatment or prevention approaches applicable to children residing in low-income urban settings. For network-wide clinical research projects and other network functions, the CAUSE-CRCs will work closely with the CAUSE Leadership Center (CAUSE-LC).

 

Link: https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-19-073.html

Application Date Line: June 19, 2020

All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s).

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date

  • Childhood Asthma in Urban Settings Clinical Research Network- Leadership Center (UM1 Clinical Trial Required)

The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for the NIAID Childhood Asthma in Urban Settings Clinical Research Network Leadership Center (CAUSE-LC). The CAUSE-LC will provide the overall scientific strategy and organizational structure to the CAUSE Clinical Research Network and will interact closely with the CAUSE Clinical Research Centers (CAUSE -CRCs) to support the conduct of multi-site clinical studies and trials with the ultimate goal of developing effective interventions or asthma prevention approaches applicable to children residing in low-income urban settings.

Link: https://grants.nih.gov/grants/guide/rfa-files/RFA-AI-19-074.html

Application Date Line: June 19, 2020

All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s).

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s).

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date

Department of Health and Human Services

This funding opportunity announcement is designed to support biomedical data repositories. Biomedical data repositories under this announcement should have the primary function to ingest, archive, preserve, manage, distribute, and make accessible the data related to a particular system or systems. Support for data curation must be limited to that which improves the efficiency and accessibility of data ingestion, management, and use and reuse by the user communities. Support for software and tool development must be limited to that which provides essential functions or significantly increases the efficiency of operation of the repository. Applications that have a significant focus on software and tool development are not appropriate for this activity.

Link: https://grants.nih.gov/grants/guide/pa-files/PAR-20-089.html

Application Date Line: January 25, 2021; September 24, 2021; January 25, 2022; September 26, 2022; January 25, 2023

All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s).

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Biomedical Knowledge base

 This funding opportunity announcement is designed to support biomedical knowledgebases. Biomedical knowledgebases under this announcement should have the primary function to extract, accumulate, organize, annotate, and link growing bodies of information related to core datasets. Support for data curation should include efficient and effective methods of curation that scale to the needs of the community and include semi-automated methods. Support for software and tool development must be limited to that which provides essential functions or significantly increases the efficiency of operation of the knowledgebase.

Applications that have a significant focus on software or tool development are not appropriate for this activity.

 

Link: https://grants.nih.gov/grants/guide/pa-files/PAR-20-097.html

Application Date Line: September 25, 2020; January 25, 2021; September 24, 2021; January 25, 2022; September 26, 2022; January 25, 2023

All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s).

Research Answers to National Cancer Institute’s (NCI) Provocative Questions

The purpose of this Funding Opportunity Announcement (FOA) is to support research projects designed to solve specific problems and paradoxes in cancer research identified by the National Cancer Institute (NCI) Provocative Questions Initiative. These problems and paradoxes phrased as questions are not intended to represent the full range of NCI’s priorities in cancer research. Rather, they are meant to challenge researchers to think about and elucidate specific problems in key areas of cancer research that are deemed important but have not received sufficient attention.

 

Some of these “Provocative Questions” (PQs) stem from intriguing but older, neglected observations that have never been adequately explored. Other PQs are built on more recent findings that are perplexing or paradoxical, revealing important gaps in current knowledge. Finally, some PQs reflect problems that traditionally have been thought to be intractable but that now may be open to investigations using new strategies and recent technical advances.

 

The current issuance of the PQ Initiative includes an updated set of 9 PQs. Each research project proposed in response to this FOA must be focused on addressing the research problems defined by a specific PQ selected from the list. Projects proposed to address PQs may use strategies that incorporate ideas and approaches from multiple disciplines, as appropriate. Transdisciplinary projects are encouraged if they serve the scientific focus of the selected PQ.

Link: https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-20-004.html

Application Date Line: November 17, 2020

No late applications will be accepted for this Funding Opportunity Announcement.

All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s).

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

New Investigator Gateway Awards for Collaborative T1D Research (R03 Clinical Trial Not Allowed)

The New Investigator Gateway Award in T1D Research is designed to ensure that a robust pipeline of talented new investigators will continue to embark on successful careers in T1D research. In addition to providing support for preliminary research, the Gateway program provides an opportunity for new Program Directors/Principal Investigators (PD/PIs) to pursue their studies within the intellectual environment of a select number of large, ongoing collaborative research programs. Embedding awardees within an established scientific framework in each of these consortia will provide unique opportunities for New and Early Stage Investigators to increase their understanding of key questions in the field, to network, and to establish unique and potentially long-lasting collaborations that will propel their careers forward. It is anticipated that the Gateway award will provide the support needed to enhance the success of future R01 submissions from New Investigators interested in pursuing careers in T1D research.

Link: https://grants.nih.gov/grants/guide/rfa-files/RFA-DK-19-026.html

Application Date Line: March 25, 2020 and November 3, 2020

All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s).

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

BRAIN Initiative: Biology and Biophysics of Neural Stimulation and Recording Technologies (R01 Clinical Trials Optional)

A central goal of the BRAIN Initiative is to develop new and improved technologies suitable for recording from as well as controlling specified cell types and circuits to modulate and understand function in the central nervous system. In order to accomplish these goals, further information is needed to understand the function of current technologies used for recording or stimulating the nervous system.

This RFA accepts grant applications in two related but distinct areas. The first is to systematically characterize, model, and validate the membrane, cellular, circuit, and adaptive-biological responses of neuronal and non-neuronal cells to various types of stimulation technologies. The second is to understand the biological and bioinformatic content of signals recorded from neuronal and non-neuronal cells and circuits. Development of new technologies, therapies and disease models is outside the scope of this FOA. Activities related to enabling the simultaneous use of multiple recording or stimulation technologies are allowed.

Link: https://grants.nih.gov/grants/guide/rfa-files/RFA-NS-20-006.html

Application Date Line: March 24, 2020, June 2, 2020, October 1, 2020, February 2, 2021, June 1, 2021, October 1, 2021, February 1, 2022, June 1, 2022, and October 3, 2022

by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates.

All applications are due by 5:00 PM local time of applicant organization. All types of non-AIDS applications allowed for this funding opportunity announcement are due on the listed date(s).

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.